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STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma

The dysregulation of glutamine metabolism provides survival advantages for tumors by supplementing tricarboxylic acid cycle. Glutamate dehydrogenase 1 (GLUD1) is one of the key enzymes in glutamine catabolism. Here, we found that enhanced protein stability was the key factor for the upregulation of...

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Detalles Bibliográficos
Autores principales: Hu, Qifan, Lei, Jiapeng, Cheng, Zhujun, Xu, Jing, Wang, Lei, Yuan, Yi, Gan, Mingxi, Wang, Yanan, Xie, Yilin, Yao, Lu, Wang, Keru, Liu, Yuhan, Xun, Wenze, Wang, Jian-Bin, Han, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319899/
https://www.ncbi.nlm.nih.gov/pubmed/37416474
http://dx.doi.org/10.1016/j.isci.2023.107151