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STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma
The dysregulation of glutamine metabolism provides survival advantages for tumors by supplementing tricarboxylic acid cycle. Glutamate dehydrogenase 1 (GLUD1) is one of the key enzymes in glutamine catabolism. Here, we found that enhanced protein stability was the key factor for the upregulation of...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319899/ https://www.ncbi.nlm.nih.gov/pubmed/37416474 http://dx.doi.org/10.1016/j.isci.2023.107151 |