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Targeting NMDA receptor in Alzheimer’s disease: identifying novel inhibitors using computational approaches

The glutamate-gated ion channels known as N-methyl-d-aspartate receptors (NMDARs) are important for both normal and pathological brain function. Subunit-selective antagonists have high therapeutic promise since many pathological conditions involve NMDAR over activation, although few clinical success...

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Detalles Bibliográficos
Autores principales: Siddiqui, Arif Jamal, Badraoui, Riadh, Jahan, Sadaf, Alshahrani, Mohammed Merae, Siddiqui, Maqsood Ahmed, Khan, Andleeb, Adnan, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319995/
https://www.ncbi.nlm.nih.gov/pubmed/37416066
http://dx.doi.org/10.3389/fphar.2023.1208968