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Targeting NMDA receptor in Alzheimer’s disease: identifying novel inhibitors using computational approaches
The glutamate-gated ion channels known as N-methyl-d-aspartate receptors (NMDARs) are important for both normal and pathological brain function. Subunit-selective antagonists have high therapeutic promise since many pathological conditions involve NMDAR over activation, although few clinical success...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319995/ https://www.ncbi.nlm.nih.gov/pubmed/37416066 http://dx.doi.org/10.3389/fphar.2023.1208968 |