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Structural insights into CED-3 activation

In Caenorhabditis elegans (C. elegans), onset of programmed cell death is marked with the activation of CED-3, a process that requires assembly of the CED-4 apoptosome. Activated CED-3 forms a holoenzyme with the CED-4 apoptosome to cleave a wide range of substrates, leading to irreversible cell dea...

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Detalles Bibliográficos
Autores principales: Li, Yini, Tian, Lu, Zhang, Ying, Shi, Yigong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320015/
https://www.ncbi.nlm.nih.gov/pubmed/37402593
http://dx.doi.org/10.26508/lsa.202302056