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3D-GNOME 3.0: a three-dimensional genome modelling engine for analysing changes of promoter-enhancer contacts in the human genome

In the current update, we added a feature for analysing changes in spatial distances between promoters and enhancers in chromatin 3D model ensembles. We updated our datasets by the novel in situ CTCF and RNAPII ChIA-PET chromatin loops obtained from the GM12878 cell line mapped to the GRCh38 genome...

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Detalles Bibliográficos
Autores principales: Wlasnowolski, Michal, Kadlof, Michal, Sengupta, Kaustav, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320091/
https://www.ncbi.nlm.nih.gov/pubmed/37158257
http://dx.doi.org/10.1093/nar/gkad354