Activity modulation of the Escherichia coli F(1)F(O) ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering

Most antimicrobial peptides (AMPs) exert their microbicidal activity through membrane permeabilization. The designed AMP EcDBS1R4 has a cryptic mechanism of action involving the membrane hyperpolarization of Escherichia coli, suggesting that EcDBS1R4 may hinder processes involved in membrane potenti...

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Detalles Bibliográficos
Autores principales: Makowski, Marcin, Almendro-Vedia, Víctor G., Domingues, Marco M., Franco, Octavio L., López-Montero, Iván, Melo, Manuel N., Santos, Nuno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320169/
https://www.ncbi.nlm.nih.gov/pubmed/37416464
http://dx.doi.org/10.1016/j.isci.2023.107004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320169/
https://www.ncbi.nlm.nih.gov/pubmed/37416464
http://dx.doi.org/10.1016/j.isci.2023.107004

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