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Classification and genetics of pediatric B-other acute lymphoblastic leukemia by targeted RNA sequencing

Acute lymphoblastic leukemia (ALL) can be classified into different subgroups based on recurrent genetic alterations. Here, targeted RNA sequencing was used to identify the novel subgroups of ALL in 144 B-other and 40 “classical” ALL samples. The classical TCF3-PBX1, ETV6-RUNX1, KMT2A-rearranged, an...

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Detalles Bibliográficos
Autores principales: Migita, Natacha Azussa, Jotta, Patrícia Yoshioka, Nascimento, Natália Paiva do, Vasconcelos, Victor Sande, Centoducatte, Gabriel Lopes, Massirer, Katlin Brauer, Azevedo, Amilcar Cardoso de, Brandalise, Silvia Regina, Yunes, José Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320209/
https://www.ncbi.nlm.nih.gov/pubmed/36848637
http://dx.doi.org/10.1182/bloodadvances.2022009179