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Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity

Organophosphates (OP) are highly toxic chemical nerve agents that have been used in chemical warfare. Currently, there are no effective medical countermeasures (MCMs) that mitigate the chronic effects of OP exposure. Oxidative stress is a key mechanism underlying OP-induced cell death and inflammati...

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Detalles Bibliográficos
Autores principales: Meyer, Christina, Rao, Nikhil S., Vasanthi, Suraj S., Pereira, Beatriz, Gage, Meghan, Putra, Marson, Holtkamp, Claire, Huss, Joselyn, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320212/
https://www.ncbi.nlm.nih.gov/pubmed/37416507
http://dx.doi.org/10.3389/fncel.2023.1195843