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NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway

NADPH oxidases 2 (NOX2) is the main source of ROS in macrophages, which plays a critical role in the formation of atherosclerosis. However, effects of NOX2 inhibition on established vulnerable plaques and the potential role involved remain unclear. The purpose of this study is to investigate the lat...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Liu, Xin-yan, Zhao, Wen-xin, Li, Fa-dong, Guo, Peng-rong, Fan, Qian, Wu, Xiao-fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320254/
https://www.ncbi.nlm.nih.gov/pubmed/37354827
http://dx.doi.org/10.1016/j.redox.2023.102763