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Identification of highly reliable risk genes for Alzheimer’s disease through joint-tissue integrative analysis

Numerous genetic variants associated with Alzheimer’s disease (AD) have been identified through genome-wide association studies (GWAS), but their interpretation is hindered by the strong linkage disequilibrium (LD) among the variants, making it difficult to identify the causal variants directly. To...

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Detalles Bibliográficos
Autores principales: Wang, Yong Heng, Luo, Pan Pan, Geng, Ao Yi, Li, Xinwei, Liu, Tai-Hang, He, Yi Jie, Huang, Lin, Tang, Ya Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320295/
https://www.ncbi.nlm.nih.gov/pubmed/37416324
http://dx.doi.org/10.3389/fnagi.2023.1183119