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Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cells

It remains uncertain how global genome nucleotide excision repair (GG-NER) efficiently removes various helix distorting DNA lesions in the cell nucleus. Here, we present a protocol to assess the contribution of factors of interest to GG-NER using two types of fluorescence-microscopy-based techniques...

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Detalles Bibliográficos
Autores principales: Kusakabe, Masayuki, Sugasawa, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320318/
https://www.ncbi.nlm.nih.gov/pubmed/37352107
http://dx.doi.org/10.1016/j.xpro.2023.102378