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Aurora kinase A regulates cancer-associated RNA aberrant splicing in breast cancer

The contribution of oncogenes to tumor-associated RNA splicing and the relevant molecular mechanisms therein require further elaboration. Here, we show that oncogenic Aurora kinase A (AURKA) promotes breast cancer-related RNA aberrant splicing in a context-dependent manner. AURKA regulated pan-breas...

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Detalles Bibliográficos
Autores principales: Li, Sisi, Qi, Yangfan, Yu, Jiachuan, Hao, Yuchao, Xu, Lingzhi, Ding, Xudong, Zhang, Minghui, Geng, Jingshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320321/
https://www.ncbi.nlm.nih.gov/pubmed/37415951
http://dx.doi.org/10.1016/j.heliyon.2023.e17386