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Selenium and zinc alleviate quaternary metal mixture -induced neurotoxicity in rats by inhibiting oxidative damage and modulating the expressions of NF-kB and Nrf2/Hmox-1 pathway

BACKGROUND: This study evaluated the potential protective effects of Zn and Se in the cerebellum and cerebral cortex, two fundamentally important brain regions, in albino rats that were exposed to heavy metals mixture (Al, Pb, Hg and Mn). METHODS: Animals were divided into five groups of seven anima...

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Detalles Bibliográficos
Autores principales: Dike, Chinyere, Orish, Chinna N., Ezejiofor, Anthonet N., Cirovic, Ana, Cirovic, Aleksandar, Babatunde, Bolaji, Sikoki, Francis, Orisakwe, Orish E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320409/
https://www.ncbi.nlm.nih.gov/pubmed/37415728
http://dx.doi.org/10.1016/j.ibneur.2023.06.003