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Heparin Prowess: Favorable Vascular–Immune Reprogramming in Pancreatic Cancer

Several approaches for overcoming immunotherapy resistance in pancreatic and colorectal cancer syngeneic models were assessed using heparin and immunotherapy. Beneficial responses were attributed to heparin-induced vascular normalization, ensuing CD8(+) T-cell infiltration, and M1 macrophage polariz...

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Detalles Bibliográficos
Autor principal: Korc, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320458/
https://www.ncbi.nlm.nih.gov/pubmed/37099035
http://dx.doi.org/10.1158/1078-0432.CCR-23-0346