Cargando…

RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer

PURPOSE: To determine the ability of RAD51 foci to predict platinum chemotherapy response in high-grade serous ovarian cancer (HGSOC) patient-derived samples. EXPERIMENTAL DESIGN: RAD51 and γH2AX nuclear foci were evaluated by immunofluorescence in HGSOC patient-derived cell lines (n = 5), organoids...

Descripción completa

Detalles Bibliográficos
Autores principales:	Compadre, Amanda J., van Biljon, Lillian N., Valentine, Mark C., Llop-Guevara, Alba, Graham, Emily, Fashemi, Bisiayo, Herencia-Ropero, Andrea, Kotnik, Emilee N., Cooper, Isaac, Harrington, Shariska P., Kuroki, Lindsay M., McCourt, Carolyn K., Hagemann, Andrea R., Thaker, Premal H., Mutch, David G., Powell, Matthew A., Sun, Lulu, Mosammaparast, Nima, Serra, Violeta, Zhao, Peinan, Lomonosova, Elena, Khabele, Dineo, Mullen, Mary M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Precision Medicine and Imaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320470/ https://www.ncbi.nlm.nih.gov/pubmed/37097615 http://dx.doi.org/10.1158/1078-0432.CCR-22-3335

Ejemplares similares

Persistent inequities in access to and continuity of gynecologic oncology care during the COVID-19 pandemic (052)
por: Bruce, Shaina, et al.
Publicado: (2022)

Inhibition of AXL and VEGF-A Has Improved Therapeutic Efficacy in Uterine Serous Cancer
por: Toboni, Michael D., et al.
Publicado: (2021)

Impact of the COVID-19 pandemic on referral to and delivery of gynecologic oncology care
por: Bruce, Shaina F., et al.
Publicado: (2022)

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival
por: Kotnik, Emilee N., et al.
Publicado: (2023)

Community access to primary care is an important geographic disparity among ovarian cancer patients undergoing cytoreductive surgery
por: Zamorano, Abigail S., et al.
Publicado: (2022)

Quantification of ovarian lesion and fallopian tube vasculature using optical-resolution photoacoustic microscopy
por: Leng, Xiandong, et al.
Publicado: (2022)

Patients with endometrial cancer continue to lack understanding of their risks for cancer
por: Sekhon, Subhjit, et al.
Publicado: (2019)

Disparities in ovarian cancer survival at the only NCI-designated cancer center in Kansas
por: Petersen, Shariska, et al.
Publicado: (2020)

Gynecologic oncology patient perspectives and knowledge on advance care planning: A quality improvement intervention
por: Huepenbecker, Sarah P., et al.
Publicado: (2022)

Obese endometrial cancer survivors’ perceptions of weight loss strategies and characteristics that may influence participation in behavioral interventions
por: Wilson, Elise M., et al.
Publicado: (2021)

Inpatient management of hypercalcemia portends a poor prognosis among gynecologic oncology patients: A trigger to initiate hospice care?
por: Cripe, James C., et al.
Publicado: (2019)

Do gynecologic oncology patients with severely diminished renal function and urinary tract obstruction benefit from ureteral stenting or percutaneous nephrostomy?
por: Liang, Brooke, et al.
Publicado: (2019)

Effects of feminine hygiene products on the vaginal mucosal biome
por: Fashemi, Bisiayo, et al.
Publicado: (2013)

Awareness of the association between obesity and peri-operative risk among newly diagnosed patients with complex atypical hyperplasia and endometrial cancer
por: Kuroki, Lindsay M., et al.
Publicado: (2015)

The role of endometrial sampling for surveillance of recurrence in postmenopausal patients with medically inoperable stage I endometrial cancer
por: Carey-Love, Angelina, et al.
Publicado: (2020)

The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
por: Khabele, Dineo
Publicado: (2014)

Radiation therapy for vaginal and perirectal lesions in recurrent ovarian cancer
por: Johns, E.A., et al.
Publicado: (2021)

CCNE1 and BRD4 co-amplification in high-grade serous ovarian cancer is associated with poor clinical outcomes
por: Petersen, Shariska, et al.
Publicado: (2020)

Heated Intraperitoneal Chemotherapy in the Management of Advanced Ovarian Cancer
por: Jewell, Andrea, et al.
Publicado: (2018)

4043 Saliva microRNA for pediatric concussion assessment
por: Hicks, Steven, et al.
Publicado: (2020)

AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer
por: Divine, Laura M., et al.
Publicado: (2016)

A Case of Extrauterine Endometrial Stromal Sarcoma in the Colon Diagnosed Three Decades after Hysterectomy for Benign Disease
por: Ayuso, Andres, et al.
Publicado: (2013)

Bipolar Tumor-Associated Macrophages in Ovarian Cancer as Targets for Therapy
por: Gupta, Vijayalaxmi, et al.
Publicado: (2018)

4429 Powering precision medicine research with the efficient construction of large diverse cohorts
por: Petukhova, Lynn, et al.
Publicado: (2020)

4058 Enhanced efficiency of large-scale clinical proteomic studies: when less is more
por: Thomas, Stefani, et al.
Publicado: (2020)

4199 A pilot randomized controlled trial of precision care for smoking cessation in the Southern Community Cohort Study
por: Senft, Nicole, et al.
Publicado: (2020)

4513 European Ancestry as a Risk Factor for Atrial Fibrillation in Puerto Rican Hispanics
por: Gonzalez-Cordero, Ariel
Publicado: (2020)

4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
por: Jenkins, Samir V, et al.
Publicado: (2020)

4089 Clinical Implementation of Monte Carlo Dose Calculation for Patient-Specific Radiotherapy Quality Assurance
por: Parenica, Holly Marie, et al.
Publicado: (2020)

4228 A latent class analysis of seriously ill adults with multiple chronic conditions receiving palliative care
por: Murali, Komal, et al.
Publicado: (2020)

4292 Epigenetic Age and Depressive Symptoms in African American Women with Cardiometabolic Conditions
por: Perez, Nicole B, et al.
Publicado: (2020)

4167 Peri-transplant Lung Microbiome Reveal Oral Bacteria, Pepsin And Inflammatory Markers Co-associate With Primary Graft Dysfunction, Implicating Aspiration As A Potential Contributor
por: McGinniss, John Evan, et al.
Publicado: (2020)

4565 Sex-Specific Differences in the Genomic Landscape of Pediatric and Adult Glioblastoma
por: Ivanov, Nikolay A., et al.
Publicado: (2020)

4106 Personalizing Care For Colorectal Cancer: Identifying Novel Opportunities
por: Rivers, Zachary, et al.
Publicado: (2020)

4482 Horizontal ridge augmentation in maxilla using bone expansion vs bone splitting techniques in adult patients: a prospective cohort
por: Acevedo, Amanda Figueroa, et al.
Publicado: (2020)

4518 Metabolomic Identifiers Predictive of Adverse Events due to Acetaminophen Administration
por: Sonn, Brandon Joseph, et al.
Publicado: (2020)

4360 Black Bone MRI from the Lab to Clinical Practice: Eliminating Radiation Exposure in Reconstructive Surgery Patients
por: Suchyta, Marissa, et al.
Publicado: (2020)

4023 Catecholamines and Opioid Therapy Requirements for the Management of Acute Post-Procedural Pain: The clinical Trend to Identify Remarkable Elements in Opioid Drug Dependency
por: Rivera, Armando Uribe, et al.
Publicado: (2020)

4061 Clinical utility of precision medicine approaches to guide anti-platelet selection for adult patients with acute coronary syndromes (ACS), following percutaneous coronary intervention (PCI)
por: Mosley, Scott, et al.
Publicado: (2020)

4385 The Pain and Social Experiences Project: Understanding the role of interpersonal trauma in pain
por: Pierce, Jennifer, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k2m5bieq7ov3nvt2l9h5rrojao