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Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma

High-risk neuroblastoma exhibits transcriptional activation of the mevalonate pathway that produces cholesterol and nonsterol isoprenoids. A better understanding of how this metabolic reprogramming contributes to neuroblastoma development could help identify potential prevention and treatment strate...

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Detalles Bibliográficos
Autores principales: Tran, Gia-Buu, Ding, Jane, Ye, Bingwei, Liu, Mengling, Yu, Yajie, Zha, Yunhong, Dong, Zheng, Liu, Kebin, Sudarshan, Sunil, Ding, Han-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
https://www.ncbi.nlm.nih.gov/pubmed/37057874
http://dx.doi.org/10.1158/0008-5472.CAN-22-3450