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Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma
High-risk neuroblastoma exhibits transcriptional activation of the mevalonate pathway that produces cholesterol and nonsterol isoprenoids. A better understanding of how this metabolic reprogramming contributes to neuroblastoma development could help identify potential prevention and treatment strate...
Autores principales: | Tran, Gia-Buu, Ding, Jane, Ye, Bingwei, Liu, Mengling, Yu, Yajie, Zha, Yunhong, Dong, Zheng, Liu, Kebin, Sudarshan, Sunil, Ding, Han-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320471/ https://www.ncbi.nlm.nih.gov/pubmed/37057874 http://dx.doi.org/10.1158/0008-5472.CAN-22-3450 |
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