Pharmacologic inhibition of glycolysis prevents the development of lupus by altering the gut microbiome in mice

Gut dysbiosis has been associated with lupus pathogenesis, and fecal microbiota transfers (FMT) from lupus-prone mice shown to induce autoimmune activation into healthy mice. The immune cells of lupus patients exhibit an increased glucose metabolism and treatments with 2-deoxy-D-glucose (2DG), a gly...

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Detalles Bibliográficos
Autores principales: Elshikha, Ahmed S., Ge, Yong, Brown, Josephine, Kanda, Nathalie, Zadeh, Mojgan, Abboud, Georges, Choi, Seung-Chul, Silverman, Gregg, Garrett, Timothy J., Clapp, William L., Mohamadzadeh, Mansour, Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320500/
https://www.ncbi.nlm.nih.gov/pubmed/37416482
http://dx.doi.org/10.1016/j.isci.2023.107122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320500/
https://www.ncbi.nlm.nih.gov/pubmed/37416482
http://dx.doi.org/10.1016/j.isci.2023.107122

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