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A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress

The nervous system participates in the initiation and modulation of systemic stress. Ionstasis is of utmost importance for neuronal function. Imbalance in neuronal sodium homeostasis is associated with pathologies of the nervous system. However, the effects of stress on neuronal Na(+) homeostasis, e...

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Detalles Bibliográficos
Autores principales: Petratou, Dionysia, Gjikolaj, Martha, Kaulich, Eva, Schafer, William, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320524/
https://www.ncbi.nlm.nih.gov/pubmed/37416472
http://dx.doi.org/10.1016/j.isci.2023.107117