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Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

OBJECTIVE: Astrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported. However, the implications of these tumor-associated reactive astrocytes (T...

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Detalles Bibliográficos
Autores principales: Zhang, Chuan-bao, Wang, Zhi-liang, Liu, Han-jie, Wang, Zheng, Jia, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320578/
https://www.ncbi.nlm.nih.gov/pubmed/37416308
http://dx.doi.org/10.3389/fneur.2023.1193844