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Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex

Within cilia, the dynein-2 complex needs to be transported as an anterograde cargo to achieve its role as a motor to drive retrograde trafficking of the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes. We previously showed that interactions of WDR60 and the DYNC2H1–DYNC...

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Detalles Bibliográficos
Autores principales: Hiyamizu, Shunya, Qiu, Hantian, Tsurumi, Yuta, Hamada, Yuki, Katoh, Yohei, Nakayama, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320715/
https://www.ncbi.nlm.nih.gov/pubmed/37309605
http://dx.doi.org/10.1242/bio.059976