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Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish

Due to its genetic amenability coupled with advances in genome editing, zebrafish is an excellent model to examine the function of (epi)genomic elements. Here, we repurposed the Ac/Ds maize transposition system to efficiently characterise zebrafish cis-regulated elements, also known as enhancers, in...

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Detalles Bibliográficos
Autores principales: Chong-Morrison, Vanessa, Mayes, Sarah, Simões, Filipa C., Senanayake, Upeka, Carroll, Dervla S., Riley, Paul R., Wilson, Stephen W., Sauka-Spengler, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320716/
https://www.ncbi.nlm.nih.gov/pubmed/37367831
http://dx.doi.org/10.1242/bio.059995