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Impaired mitochondrial dynamics and removal of the damaged mitochondria in diabetic retinopathy

INTRODUCTION: Mitochondrial dynamic plays a major role in their quality control, and the damaged mitochondrial components are removed by autophagy. In diabetic retinopathy, mitochondrial fusion enzyme, mitofusin 2 (Mfn2), is downregulated and mitochondrial dynamic is disturbed resulting in depolariz...

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Detalles Bibliográficos
Autores principales: Alka, Kumari, Kumar, Jay, Kowluru, Renu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320727/
https://www.ncbi.nlm.nih.gov/pubmed/37415667
http://dx.doi.org/10.3389/fendo.2023.1160155