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Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression

BACKGROUNDS AND AIMS: As a central event during liver fibrosis, hepatic stellate cells (HSC) have been thought to be a potential therapeutic target for liver fibrosis. Previous studies have shown that runt‐related transcription factor 2 (Runx2) is associated with the development of non‐alcoholic fat...

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Detalles Bibliográficos
Autores principales: Zhong, Li, Zhao, Jinqiu, Huang, Lu, Liu, Yi, Pang, Xiaoxiao, Zhan, Ke, Li, Shan, Xue, Qian, Pan, Xiaoli, Deng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320748/
https://www.ncbi.nlm.nih.gov/pubmed/37403784
http://dx.doi.org/10.1002/ctm2.1316