A structural blueprint for interleukin-21 signal modulation

Interleukin-21 (IL-21) plays a critical role in generating immunological memory by promoting the germinal center reaction, yet clinical use of IL-21 remains challenging because of its pleiotropy and association with autoimmune disease. To better understand the structural basis of IL-21 signaling, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Abhiraman, Gita C., Bruun, Theodora U.J., Caveney, Nathanael A., Su, Leon L., Saxton, Robert A., Yin, Qian, Tang, Shaogeng, Davis, Mark M., Jude, Kevin M., Garcia, K. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320830/
https://www.ncbi.nlm.nih.gov/pubmed/37339051
http://dx.doi.org/10.1016/j.celrep.2023.112657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320830/
https://www.ncbi.nlm.nih.gov/pubmed/37339051
http://dx.doi.org/10.1016/j.celrep.2023.112657

Ejemplares similares