Wird geladen …
Protocadherin 20 maintains intestinal barrier function to protect against Crohn’s disease by targeting ATF6
BACKGROUND: Intestinal barrier dysfunction plays a central role in the pathological onset of Crohn’s disease. We identify the cadherin superfamily member protocadherin 20 (PCDH20) as a crucial factor in Crohn’s disease. Here we describe the function of PCDH20 and its mechanisms in gut homeostasis, b...
Hauptverfasser: | , , , , , , , , , , , , , |
---|---|
Format: | Online Artikel Text |
Sprache: | English |
Veröffentlicht: |
BioMed Central
2023
|
Schlagworte: | |
Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320870/ https://www.ncbi.nlm.nih.gov/pubmed/37407995 http://dx.doi.org/10.1186/s13059-023-02991-0 |