Optogenetic dissection of RET signaling reveals robust activation of ERK and enhanced filopodia-like protrusions of regenerating axons

RET (REarranged during Transfection) is a receptor tyrosine kinase that transduces various external stimuli into biological functions, such as survival and differentiation, in neurons. In the current study, we developed an optogenetic tool for modulating RET signaling, termed optoRET, combining the...

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Detalles Bibliográficos
Autores principales: Hyeon, Bobae, Lee, Heeyoung, Kim, Nury, Heo, Won Do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320947/
https://www.ncbi.nlm.nih.gov/pubmed/37403137
http://dx.doi.org/10.1186/s13041-023-01046-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320947/
https://www.ncbi.nlm.nih.gov/pubmed/37403137
http://dx.doi.org/10.1186/s13041-023-01046-6

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