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FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1–YTHDF2 dependent manner

BACKGROUND: Adolescent idiopathic scoliosis (AIS) is characterized by low lean mass without vertebral deformity. The cause-and-effect relationship between scoliosis and paraspinal muscle imbalance has long puzzled researchers. Although FTO has been identified as a susceptibility gene for AIS, its po...

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Detalles Bibliográficos
Autores principales: Wang, Wengang, Du, Xueming, Luo, Ming, Yang, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320966/
https://www.ncbi.nlm.nih.gov/pubmed/37408034
http://dx.doi.org/10.1186/s13148-023-01526-5