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Rheumatoid arthritis macrophages are primed for inflammation and display bioenergetic and functional alterations

OBJECTIVES: Myeloid cells with a monocyte/macrophage phenotype are present in large numbers in the RA joint, significantly contributing to disease; however, distinct macrophage functions have yet to be elucidated. This study investigates the metabolic activity of infiltrating polarized macrophages a...

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Detalles Bibliográficos
Autores principales: Hanlon, Megan M, McGarry, Trudy, Marzaioli, Viviana, Amaechi, Success, Song, Qingxuan, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321118/
https://www.ncbi.nlm.nih.gov/pubmed/36398893
http://dx.doi.org/10.1093/rheumatology/keac640