Cargando…
Rheumatoid arthritis macrophages are primed for inflammation and display bioenergetic and functional alterations
OBJECTIVES: Myeloid cells with a monocyte/macrophage phenotype are present in large numbers in the RA joint, significantly contributing to disease; however, distinct macrophage functions have yet to be elucidated. This study investigates the metabolic activity of infiltrating polarized macrophages a...
Autores principales: | Hanlon, Megan M, McGarry, Trudy, Marzaioli, Viviana, Amaechi, Success, Song, Qingxuan, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321118/ https://www.ncbi.nlm.nih.gov/pubmed/36398893 http://dx.doi.org/10.1093/rheumatology/keac640 |
Ejemplares similares
-
Rheumatoid arthritis CD14(+) monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease
por: McGarry, Trudy, et al.
Publicado: (2021) -
ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis
por: Floudas, Achilleas, et al.
Publicado: (2021) -
Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis
por: McGarry, Trudy, et al.
Publicado: (2015) -
Dysregulated bioenergetics: a key regulator of joint inflammation
por: Biniecka, M, et al.
Publicado: (2016) -
The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis
por: Orr, Carl K., et al.
Publicado: (2018)