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Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents

Although the etiology of major depressive disorder remains poorly understood, reduced gamma oscillations is an emerging biomarker. Olfactory bulbectomy, an established model of depression that reduces limbic gamma oscillations, suffers from non-specific effects of structural damage. Here, we show th...

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Detalles Bibliográficos
Autores principales: Li, Qun, Takeuchi, Yuichi, Wang, Jiale, Gellért, Levente, Barcsai, Livia, Pedraza, Lizeth K., Nagy, Anett J., Kozák, Gábor, Nakai, Shinya, Kato, Shigeki, Kobayashi, Kazuto, Ohsawa, Masahiro, Horváth, Gyöngyi, Kékesi, Gabriella, Lőrincz, Magor L., Devinsky, Orrin, Buzsáki, György, Berényi, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321244/
https://www.ncbi.nlm.nih.gov/pubmed/37164008
http://dx.doi.org/10.1016/j.neuron.2023.04.013