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A Novel Isotope-labeled Small Molecule Probe CC12 for Anti-glioma via Suppressing LYN-mediated Progression and Activating Apoptosis Pathways

Background: Glioblastoma multiforme (GBM) is the most lethal malignancy in brain, which is surrounded by the blood-brain barrier (BBB), which limits the efficacy of standard treatments. Developing an effective drug that can penetrate the blood-brain barrier (BBB) remains a critical challenge in the...

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Detalles Bibliográficos
Autores principales: Huang, Hsu-Shan, Chiang, I-Tsang, Lawal, Bashir, Weng, Yueh-Shan, Jeng, Long-Bin, Kuo, Yu-Cheng, Liu, Yu-Chang, Hsu, Fei-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321274/
https://www.ncbi.nlm.nih.gov/pubmed/37416766
http://dx.doi.org/10.7150/ijbs.82266