Tofacitinib, a suppressor of NOD2 expression, is a potential treatment for Blau syndrome

INTRODUCTION: Blau syndrome is a rare autosomal dominant autoinflammatory granulomatous disease caused by a mutation in the NOD2 gene. It is characterized by a clinical trial of granulomatous dermatitis, arthritis, and uveitis. Tofacitinib is a pan Janus kinase (JAK) inhibitor used for treatment of...

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Detalles Bibliográficos
Autores principales: Ueki, Yoko, Takimoto-Ito, Riko, Saito, Megumu K., Tanizaki, Hideaki, Kambe, Naotomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321295/
https://www.ncbi.nlm.nih.gov/pubmed/37415984
http://dx.doi.org/10.3389/fimmu.2023.1211240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321295/
https://www.ncbi.nlm.nih.gov/pubmed/37415984
http://dx.doi.org/10.3389/fimmu.2023.1211240

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