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Dysregulated NAD(H) homeostasis associated with ciprofloxacin tolerance in Escherichia coli investigated on a single-cell level with the Peredox [NADH:NAD+] biosensor

INTRODUCTION: Antibiotic persistence (subpopulation tolerance) occurs when a subpopulation of antibiotic sensitive cells survives prolonged exposure to a bactericidal concentration of an antibiotic, and is capable of regrowth once the antibiotic is removed. This phenomenon has been shown to contribu...

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Detalles Bibliográficos
Autores principales: Urbaniec, Joanna, Sanderson-Smith, Martina, McFadden, Johnjoe, Hai, Faisal I., Hingley-Wilson, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321300/
https://www.ncbi.nlm.nih.gov/pubmed/37415820
http://dx.doi.org/10.3389/fmicb.2023.1191968