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Local solvation structures govern the mixing thermodynamics of glycerol–water solutions

Glycerol is a major cryoprotective agent and is widely used to promote protein stabilization. By a combined experimental and theoretical study, we show that global thermodynamic mixing properties of glycerol and water are dictated by local solvation motifs. We identify three hydration water populati...

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Detalles Bibliográficos
Autores principales: Das Mahanta, Debasish, Brown, Dennis Robinson, Pezzotti, Simone, Han, Songi, Schwaab, Gerhard, Shell, M. Scott, Havenith, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321518/
https://www.ncbi.nlm.nih.gov/pubmed/37416713
http://dx.doi.org/10.1039/d3sc00517h