Nucleic acid sensor STING drives remodeling and its inhibition enhances steroid responsiveness in chronic obstructive pulmonary disease

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is progressive and irreversible chronic lung inflammatory disease. Cigarette smoke, the main cause of COPD, is often associated with double-stranded DNA release which potentially activates DNA-sensing pathways, such as STING. This study, there...

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Detalles Bibliográficos
Autores principales: Mdkhana, Bushra, Saheb Sharif-Askari, Narjes, Ramakrishnan, Rakhee K., Al-Sheakly, Baraa Khalid, Hafezi, Shirin, Saheb Sharif-Askari, Fatemeh, Bajbouj, Khuloud, Hamid, Qutayba, Halwani, Rabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321631/
https://www.ncbi.nlm.nih.gov/pubmed/37406004
http://dx.doi.org/10.1371/journal.pone.0284061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321631/
https://www.ncbi.nlm.nih.gov/pubmed/37406004
http://dx.doi.org/10.1371/journal.pone.0284061

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