XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively

XIAP is an endogenous inhibitor of cell death and inactivating mutations of XIAP are responsible for X-linked lymphoproliferative disease (XLP-2) and primary immunodeficiency, but the mechanism(s) behind these contradictory outcomes have been unclear. We report that during infection of macrophages a...

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Detalles Bibliográficos
Autores principales: Thakker, Parva, Ariana, Ardeshir, Hajjar, Stephanie, Cai, David, Rijal, Dikchha, Sad, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321636/
https://www.ncbi.nlm.nih.gov/pubmed/37347786
http://dx.doi.org/10.1371/journal.ppat.1011455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321636/
https://www.ncbi.nlm.nih.gov/pubmed/37347786
http://dx.doi.org/10.1371/journal.ppat.1011455

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