Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions

Legionella pneumophila is a natural pathogen of amoebae that causes Legionnaires’ Disease in immunocompromised individuals via replication within macrophages. L. pneumophila virulence and intracellular replication hinges on hundreds of Dot/Icm-translocated effector proteins, which are essential for...

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Detalles Bibliográficos
Autores principales: Ngwaga, Tshegofatso, Chauhan, Deepika, Salberg, Abigail G., Shames, Stephanie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321654/
https://www.ncbi.nlm.nih.gov/pubmed/37347796
http://dx.doi.org/10.1371/journal.ppat.1011473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321654/
https://www.ncbi.nlm.nih.gov/pubmed/37347796
http://dx.doi.org/10.1371/journal.ppat.1011473

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