MK2 drives progression of pancreas and colon cancers by suppressing CD8(+) T cell cytotoxic function and is a potential immunotherapy target

BACKGROUND: Immune cell composition is a critical and dynamic component of the tumor microenvironment, which has an impact on immunosuppression and progression of cancer. T cells, especially CD8(+) T cells, are one of the major immune cell types responsible for tumor cell killing employing receptor-...

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Detalles Bibliográficos
Autores principales: Jacenik, Damian, Lebish, Eric J., Beswick, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321668/
https://www.ncbi.nlm.nih.gov/pubmed/37415974
http://dx.doi.org/10.3389/fimmu.2023.1212100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321668/
https://www.ncbi.nlm.nih.gov/pubmed/37415974
http://dx.doi.org/10.3389/fimmu.2023.1212100

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