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MK2 drives progression of pancreas and colon cancers by suppressing CD8(+) T cell cytotoxic function and is a potential immunotherapy target
BACKGROUND: Immune cell composition is a critical and dynamic component of the tumor microenvironment, which has an impact on immunosuppression and progression of cancer. T cells, especially CD8(+) T cells, are one of the major immune cell types responsible for tumor cell killing employing receptor-...
Autores principales: | Jacenik, Damian, Lebish, Eric J., Beswick, Ellen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321668/ https://www.ncbi.nlm.nih.gov/pubmed/37415974 http://dx.doi.org/10.3389/fimmu.2023.1212100 |
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