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Human abdominal subcutaneous-derived active beige adipocytes carrying FTO rs1421085 obesity-risk alleles exert lower thermogenic capacity

Introduction: White adipocytes store lipids, have a large lipid droplet and few mitochondria. Brown and beige adipocytes, which produce heat, are characterized by high expression of uncoupling protein (UCP) 1, multilocular lipid droplets, and large amounts of mitochondria. The rs1421085 T-to-C singl...

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Detalles Bibliográficos
Autores principales: Vámos, Attila, Arianti, Rini, Vinnai, Boglárka Ágnes, Alrifai, Rahaf, Shaw, Abhirup, Póliska, Szilárd, Guba, Andrea, Csősz, Éva, Csomós, István, Mocsár, Gábor, Lányi, Cecilia, Balajthy, Zoltán, Fésüs, László, Kristóf, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321670/
https://www.ncbi.nlm.nih.gov/pubmed/37416800
http://dx.doi.org/10.3389/fcell.2023.1155673