Endoplasmic stress sensor Ire1 is involved in cytosolic/nuclear protein quality control in Pichia pastoris cells independent of HAC1

In eukaryotic species, dysfunction of the endoplasmic reticulum (ER), namely, ER stress, provokes a cytoprotective transcription program called the unfolded protein response (UPR). The UPR is triggered by transmembrane ER-stress sensors, including Ire1, which acts as an endoribonuclease to splice an...

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Detalles Bibliográficos
Autores principales: Fauzee, Yasmin Nabilah Binti Mohd, Yoshida, Yuki, Kimata, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321714/
https://www.ncbi.nlm.nih.gov/pubmed/37415818
http://dx.doi.org/10.3389/fmicb.2023.1157146