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Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling

The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles into capsid-like structures harboring Arc mRNA. Arc capsi...

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Detalles Bibliográficos
Autores principales: Avallone, Martino, Pardo, Joaquín, Mergiya, Tadiwos F., Rájová, Jana, Räsänen, Atte, Davidsson, Marcus, Åkerblom, Malin, Quintino, Luis, Kumar, Darshan, Bramham, Clive R., Björklund, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321715/
https://www.ncbi.nlm.nih.gov/pubmed/37415832
http://dx.doi.org/10.3389/fnmol.2023.1140785