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Comprehensive Genomic Profiling of NF2-Mutated Kidney Tumors Reveals Potential Targets for Therapy

Genomic alterations (GA) in NF2 tumor-suppressor gene have been associated with aggressive behavior in kidney tumors. We used comprehensive genomic profiling (CGP) to evaluate the frequencies of NF2 GA in histologic subtypes of kidney tumors and co-occurring GA in other genes and biomarkers. Advance...

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Detalles Bibliográficos
Autores principales: Hacking, Sean M, Pavlick, Dean, Wang, Yihong, Carneiro, Benedito A, Mullally, Matthew, Lu, Shaolei, Canepa, Mariana, Bratslavsky, Gennady, Jacob, Joseph, Necchi, Andrea, Spiess, Philippe E, Wang, Li, Yakirevich, Evgeny, Ross, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322144/
https://www.ncbi.nlm.nih.gov/pubmed/36917021
http://dx.doi.org/10.1093/oncolo/oyad040