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Cell detoxification of secondary metabolites by P4-ATPase-mediated vesicle transport

Mechanisms for cellular detoxification of drug compounds are of significant interest in human health. Cyclosporine A (CsA) and tacrolimus (FK506) are widely known antifungal and immunosuppressive microbial natural products. However, both compounds can result in significant side effects when used as...

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Detalles Bibliográficos
Autores principales: Li, Yujie, Ren, Hui, Wang, Fanlong, Chen, Jianjun, Ma, Lian, Chen, Yang, Li, Xianbi, Fan, Yanhua, Jin, Dan, Hou, Lei, Zhou, Yonghong, Keyhani, Nemat O, Pei, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322151/
https://www.ncbi.nlm.nih.gov/pubmed/37405392
http://dx.doi.org/10.7554/eLife.79179