Cargando…

Perampanel ameliorates nitroglycerin-induced migraine through inhibition of the cAMP/PKA/CREB signaling pathway in the trigeminal ganglion in rats

BACKGROUND: Perampanel, a highly selective glutamate AMPA receptor antagonist, is widely used to treat epilepsy. Since the existence of common pathophysiological features between epilepsy and migraine, the aim of this study was to investigate whether perampanel could exert an antimigraine effect. ME...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhai, QingLing, Wang, KaiXin, Zhang, Defu, Chen, Jinbo, Dong, XiaoMeng, Pan, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322658/
https://www.ncbi.nlm.nih.gov/pubmed/37394274
http://dx.doi.org/10.3344/kjp.23039