Antisense oligodeoxynucleotides against dynamin-related protein 1 reduce remifentanil-induced hyperalgesia by modulating spinal N-methyl-D-aspartate receptor expression in rats

BACKGROUND: Spinal N-methyl-D-aspartate (NMDA) receptor activation is attributed to remifentanil-induced hyperalgesia (RIH). However, the specific mechanism and subsequent treatment is still unknown. Previous studies have shown that the dynamin-related protein 1 (DRP1)-mitochondria-reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Zhou, Songyi, Pan, Yizhao, Zhang, Yan, Gu, Lijun, Ma, Leikai, Xu, Qingqing, Wang, Weijian, Sun, Jiehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Experimental Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322665/
https://www.ncbi.nlm.nih.gov/pubmed/37183652
http://dx.doi.org/10.7910/DVN/EJ82IJ.

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322665/
https://www.ncbi.nlm.nih.gov/pubmed/37183652
http://dx.doi.org/10.7910/DVN/EJ82IJ.

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