Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding

Central glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) signaling is critical in GIP-based therapeutics’ ability to lower body weight, but pathways leveraged by GIPR pharmacology in the brain remain incompletely understood. We explored the role of Gipr neurons in the hypothalamus...

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Detalles Bibliográficos
Autores principales: Adriaenssens, Alice, Broichhagen, Johannes, de Bray, Anne, Ast, Julia, Hasib, Annie, Jones, Ben, Tomas, Alejandra, Burgos, Natalie Figueredo, Woodward, Orla, Lewis, Jo, O’Flaherty, Elisabeth, El, Kimberley, Cui, Canqi, Harada, Norio, Inagaki, Nobuya, Campbell, Jonathan, Brierley, Daniel, Hodson, David J., Samms, Ricardo, Gribble, Fiona, Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322681/
https://www.ncbi.nlm.nih.gov/pubmed/37212283
http://dx.doi.org/10.1172/jci.insight.164921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322681/
https://www.ncbi.nlm.nih.gov/pubmed/37212283
http://dx.doi.org/10.1172/jci.insight.164921

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