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Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway

The prevalence of obesity and type 2 diabetes is growing at an alarming rate, including among pregnant women. Low-calorie sweeteners (LCSs) have increasingly been used as an alternative to sugar to deliver a sweet taste without the excessive caloric load. However, there is little evidence regarding...

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Detalles Bibliográficos
Autores principales: Park, Soyoung, Belfoul, Amine M., Rastelli, Marialetizia, Jang, Alice, Monnoye, Magali, Bae, Hosung, Kamitakahara, Anna, Giavalisco, Patrick, Sun, Shan, Barelle, Pierre-Yves, Plows, Jasmine, Jang, Cholsoon, Fodor, Anthony, Goran, Michael I., Bouret, Sebastien G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322686/
https://www.ncbi.nlm.nih.gov/pubmed/37014702
http://dx.doi.org/10.1172/jci.insight.156397