Cargando…

HEY1-NCOA2 expression modulates chondrogenic differentiation and induces mesenchymal chondrosarcoma in mice

Mesenchymal chondrosarcoma affects adolescents and young adults, and most cases usually have the HEY1::NCOA2 fusion gene. However, the functional role of HEY1-NCOA2 in the development and progression of mesenchymal chondrosarcoma remains largely unknown. This study aimed to clarify the functional ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Miwa, Homme, Mizuki, Teramura, Yasuyo, Kumegawa, Kohei, Yamazaki, Yukari, Yamashita, Kyoko, Osato, Motomi, Maruyama, Reo, Nakamura, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322689/
https://www.ncbi.nlm.nih.gov/pubmed/37212282
http://dx.doi.org/10.1172/jci.insight.160279